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Plasma B-Type Natriuretic Peptide Levels May Increase Because of Fat Mass Loss by Metformin or Sodium-Glucose Transporter 2 Inh

Endocrinology
Author
Hamasaki et al.
Used Parameters : SMM, BFM, VFA
Publication Year : 2016
Country : Japan
Journal : Journal of Endocrinology and Metabolism
Background: Cardiovascular disease (CVD) is the leading cause of death in type 2 diabetes. Metformin reduces cardiovascular events in obese patients with type 2 diabetes, and sodium-glucose transporter 2 (SGLT2) inhibitors decrease cardiovascular events in type 2 diabetic patients with established CVD. However, the underlying mechanisms behind the cardioprotective effects of metformin and SGLT2 inhibitors are unknown. Methods: Fifteen patients with newly diagnosed type 2 diabetes receiving metformin monotherapy, and seven …
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