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Study protocol for the effects of formula diet with dapagliflozin on metabolic improvement and body composition in type 2 diabe
Nutrition | BFM | Y Watanabe et al. | 2018 | Japan | Diabetes Therapy
Introduction Sodium-dependent glucose transporter-2 (SGLT2) inhibitors such as dapagliflozin induce weight loss, but the mechanism is thought to involve loss of both body fat and skeletal muscle mass. The decrease in skeletal muscle mass may lead to worsening of insulin resistance in type 2 diabetes patients. On the other hand, formula diet (FD) is a low-calorie food containing low carbohydrates, low fat, and sufficient protein, vitamins, and minerals to support a healthy and balanced diet, and is used for the treatment of obesity or …
Acute effect of L-carnitine supplements on lactate, glucose, saturated oxygen and VO2max Variations in young males
Nutrition | PBF | Majid Kashef, Mohammad Amin Saei | 2017 | Iran | International Journal of Basic Science in Medicine
Introduction: L-carnitine may improve athlete's performance by increasing lipids oxidation. The goal of the present study was to assess the acute impact of L-carnitine supplements on lactate, glucose, saturated oxygen and VO 2 max levels in young men. Methods: Ten young males completed 2 sessions of exhausting exercise (Bruce test). In the first session, the participants consumed placebo and in the second session, they consumed 3 g of L-carnitine 90 minutes before the test. The 2 sessions were 1-week apart. Then dependent parameters …
The value of grip test, lysophosphatidlycholines, glycerophosphocholine, ornithine, glucuronic acid decrement in assessment of
Nutrition | SMM, BFM, Protein | Ye Q et al. | 2017 | China | PLoS One
The liver is essential for the regulation of energy, protein and amino acids, as well as in other aspects of metabolism. To identify efficient indexes for evaluation of nutritional status and metabolic characteristics during different Child-Pugh stages of hepatitis B cirrhosis, 83 patients and 35 healthy individuals were enrolled in our study. We found that grip strength, triceps skinfold thickness (TSF), body fat and skeletal muscle of the patients were reduced compared to the control group (P< 0.05). Ultra-high-performance liquid chromatography …
Isolated colonic Crohn's disease is associated with a reduced response to exclusive enteral nutrition compared to ileal or ileo
Nutrition | BMI, FFMI | Xu Y, et al. | 2018 | China | Clinical Nutrition
Background & aims Exclusive enteral nutrition (EEN) as a primary therapy is safe and effective for inducing the clinical remission of active luminal Crohn's disease (CD). Whether isolated colonic involvement affects the efficacy of EEN is controversial. We aimed to identify the influence of isolated colonic CD on the efficacy of EEN and to determine other potential predictors of the response to induction therapy with EEN in adult patients with CD. Methods Data for adult CD patients treated with EEN as an induction therapy at our centre from …
Effects of a meal replacement on body composition and metabolic parameters among subjects with overweight or obesity
Nutrition | BW, BMI, TBW, ICW, ECW, FFM, BFM, VFA, BCM, BMR, WHR | X Guo et al. | 2018 | China | Journal of Obesity
Meal replacement plans are effective tools for weight loss and improvement of various clinical characteristics but not sustainable due to the severe energy restriction. The aim of the study was to evaluate the impact of meal replacement, specifically 388 kcal in total energy, on body composition and metabolic parameters in individuals with overweight and obesity from a Chinese population. A parallel, randomized controlled trial was performed with 174 participants (ChiCTR-OOC-17012000). The intervention group () was provided with …
Dietary Supplementation with Curcumin Reduce Circulating Levels of Glycogen Synthase Kinase-3β and Islet Amyloid Polypeptide in
Nutrition | MM, BFM, PBF | Thota et al. | 2020 | Australia | Nutrients
Dietary supplementation with curcumin has been previously reported to have beneficial effects in people with insulin resistance, type 2 diabetes (T2D) and Alzheimer's disease (AD). This study investigated the effects of dietary supplementation with curcumin on key peptides implicated in insulin resistance in individuals with high risk of developing T2D. Plasma samples from participants recruited for a randomised controlled trial with curcumin (180 mg/day) for 12 weeks were analysed for circulating glycogen synthase kinase-3 β (GSK …
Effect of Lactobacillus gasseri BNR17 on overweight and obese adults: a randomized, double-blind clinical trial
Nutrition | SMM, BFM | Seung-Pil Jung et al. | 2013 | Korea | Korean Journal of Family Medicine
Background Lactobacillus gasseri BNR17 is a type of probiotic strain isolated from human breast milk. A study was reported regarding the fact that BNR17 was an inhibitor of obesity and diabetic activities in the human body through previous animal experiments. This study was furthered to investigate the effect of BNR17, a probiotic strain isolated from human breast milk, on obese and overweight adults. Methods Sixty-two obese volunteers aged 19 to 60 with body mass index≥ 23 kg/m 2 and fasting blood sugar≥ 100 mg/dL participated in …
The relationship between the leptin/ghrelin ratio and meals with various macronutrient contents in men with different nutrition
Nutrition | PBF | Adamska-Patruno et al. | 2018 | Poland | Nutrition Journal
Hormones, which influence satiety and hunger, play a significant role in body energy balance regulation. Ghrelin is a peptide that plays an important role in short-term appetite regulation, whereas leptin is a factor that controls long-term energy balance and is considered as a satiety hormone. The aim of this study was to evaluate the leptin/ghrelin ratio in a fasting state and after the intake of meals with varying macronutrient contents and to assess the possible differences between normal body weight and overweight/obese men …
Prolonged collagen peptide supplementation and resistance exercise training affects body composition in recreationally active m
Nutrition | BW, FFM, BFM | Kirmse et al. | 2019 | Germany | Nutrients
We aimed to determine the effects of long-term collagen peptide (CP) supplementation and resistance exercise training (RET) on body composition, strength, and muscle fiber cross-sectional area (fCSA) in recreationally active men. Fifty-seven young men were randomly and double-blinded divided into a group receiving either collagen peptides (COL, 15 g/day) or a placebo (PLA). Strength testing, bioimpedance analysis, and muscle biopsies were used prior to and after an RET intervention. Food record protocols were performed during …