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Apelin, an active endogenous peptide, has been recently receiving great attention as a promising target for antiaging intervention, primarily based on results from genetically altered mice. To validate previous experimental data and investigate the possible role of apelin in humans, in this study, we examined serum apelin level in relation to frailty and its associated parameters in a cohort of ambulatory, community-dwelling older adults. Blood samples were collected from 80 participants who underwent a comprehensive geriatric …

This study examined the effects of whey protein supplementation, compared with an isocaloric carbohydrate beverage and water, consumed immediately following an intense swimming trial on bone turnover in adolescent swimmers. Fifty-eight (31 female, 27 male) swimmers (14.1±0.4 years) were stratified into three groups matched for age, sex and body mass. The protein and carbohydrate groups consumed two isocaloric post-exercise beverages each containing 0.3 g. kg− 1 of whey protein (with~ 6 mg of calcium) or …

Background Dyslipidaemias result from the interaction between genetic and environmental factors, including diet disequilibrium and physical inactivity. Among the genetic factors associated with serum lipids, the Taq1B CETP polymorphism has been investigated. The B1 allele has been considered as a risk factor for dyslipidaemia because of its association with greater CETP levels and higher serum triglycerides. The present study aimed to determine the role of the Taq1B polymorphism with lipid and anthropometric variables and its …

Objective FTO (fat mass and obesity‐associated) gene is a well‐known genetic risk factor for obesity. We investigated whether physical activity modulates the effect of FTO rs9939609 on obesity in Korean population. Methods The study analyzed the correlation between physical activity and obesity in 8840 individuals representing the Korea Association Resource (KARE). The association between obesity‐related traits and single‐nucleotide polymorphisms (SNPs) was assessed using linear regression models. Physical activity was …

Aims: This study aims to analyze the influence of adventure race disciplines on the overall performance during 35 to 50-km competitions. Methods: Twenty-four athletes from twelve teams were studied during the second (Jacarei-SP, Brazil, 44.5-km) and fourth (Passa Quatro-MG, Brazil, 37.1-km) races of the 2015 Haka Race Series, which comprised Brazilian Adventure Race Ranking. We analysed the relationship between disciplines velocities and overall race velocity of the teams during each competition. Results: We observed the race …

This study aimed to examine differences between sexes in thermoregulatory responses and exercise time after ice slurry ingestion in a hot environment. Twenty-four healthy adults (male n= 12, body weight (BW)= 65.8±10.3; female n= 12, BW= 58.2±10.0) ingested 7.5 g/kg of either ice slurry at− 1° C (ICE) or control water at 20° C (CON) before cycling at 55% VO 2 max in a hot environment (controlled at 38° C, 40% relative humidity). Rectal (Tre) and skin (Tsk) temperature, heart rate, sweat rate, respiratory gases, ratings of thermal sensation …

This study investigated the effect of concurrent training (CT) sequences on fibroblast growth factor 21 (FGF21), irisin, myostatin (MSTN), and follistatin (FST) among adults with type 2 diabetes mellitus (T2DM). Fifty-one diabetic men were randomly selected and assigned to concurrent aerobic-resistance (AR) training and concurrent resistance-aerobic (RA) training, and non-exercise control (CON) groups. The training protocols consisted of three sessions per week for 12 weeks. The AR and RA groups received the same CT protocols and …

For the evaluation of iron nutrition status, the measurement of serum ferritin levels is the most convenient and widely used technique for estimating stored iron. However, the cut-off value of serum ferritin for iron deficiency in athletes has not yet established. This study aimed to determine the cut-off value of serum ferritin to define iron deficiency in male college student runners. This study included 37–43 Japanese male college student runners for each month. Anthropometric measurements and blood collection were conducted from March to …

Abstract Background & Aims The association between nonalcoholic fatty liver disease (NAFLD) and pulmonary function remains elusive because of the heterogeneous spectrum and inaccurate diagnostic methods of NAFLD, and insufficient pulmonary function data. We conducted this study to identify the association between histological severity of NAFLD and pulmonary function. Methods This study included patients≥ 18 years old with baseline pulmonary function data between August 2014 and July 2019 within a biopsy‐evaluated …