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Comparison of predicted energy expenditure in Japanese patients with non-alcoholic fatty liver disease to establish a suitable
Hepatology | SMM, BFM | Endo K et al. | 2016 | Japan | Journal of Nutritional Science and Vitaminology
The incidence of non-alcoholic fatty liver disease (NAFLD) is increasing in Western and Asian countries, including Japan. NAFLD includes the condition of nonalcoholic steatohepatitis, which can progress to end-stage liver disease. Weight reduction based on basal energy expenditure (BEE) is considered to be the only established treatment for patients with NAFLD. However, a formula that is suitable for predicting BEE in Japanese patients with NAFLD remains to be determined. We enrolled 77 Japanese patients who …
Characteristics of non‐alcoholic steatohepatitis among lean patients in Japan: not uncommon and not always benign
Hepatology | Segmental FFM, SMI, BFM | M Tobari et al. | 2018 | Japan | Journal of Gastroenterology and Hepatology
Abstract Background and Aim To elucidate features of nonobese non‐alcoholic fatty liver disease (NAFLD), we assessed Japanese patients with NAFLD stratified by body mass index (BMI) and by sex. Methods Biopsy‐proven 762 NAFLD patients (404 men) were classified into three groups by the Japanese criteria: nonobese group (BMI< 25 kg/m2), obese group (25 to 30), and severely obese group (≥ 30). Clinicopathological features and single nucleotide polymorphism of patatin‐like phospholipase 3 (PNPLA3) rs738409 were …
Value of the extracellular water ratio for assessment of cirrhotic patients with and without ascites
Hepatology | TBW | Nagisa Hara et al. | 2009 | Japan | Hepatology Research
Aims: Ascites, which often complicates liver cirrhosis, is reported to be a factor that worsens the outcome. The aims of this study were to quantify body water compartment changes in cirrhotic patients, with and without ascites, and to elucidate the value of body water analysis for predicting the development of ascites. Methods: A total of 109 cirrhotic patients, with and without ascites, and 65 controls were studied. Intra‐and extracellular water (ECW) in the whole body and in the arm, leg and trunk were measured using the recently developed 8 …
Insulin resistance increases loss of antibody to hepatitis B surface antigen in nondiabetic healthy adults
Hepatology | PBF | Joo EJ et al. | 2016 | Korea | Journal of Viral Hepatitis
The aim of this study was to evaluate the impact of insulin resistance on the persistence of a protective level of anti‐HB s (hepatitis B surface antigen) in a nondiabetic general population. A cohort study was designed comprising of 38 473 Korean men and women with anti‐HB s at concentrations≥ 10 mIU/mL, who underwent a health examination. Insulin resistance was assessed with a homoeostasis model assessment of insulin resistance (HOMA‐IR). A decline in anti‐HB s to< 10 mIU/L during the follow‐up was considered to be …
Relationship between relative skeletal muscle mass and nonalcoholic fatty liver disease: a 7‐year longitudinal study
Hepatology | Segmenta, FFM, SMI | KIM ET AL. | 2018 | Korea | Hepatology
Nonalcoholic fatty liver disease (NAFLD) has been associated with relative skeletal muscle mass in several cross‐sectional studies. We explored the effects of relative skeletal muscle mass and changes in relative muscle mass over time on the development of incident NAFLD or the resolution of baseline NAFLD in a large, longitudinal, population‐based 7‐year cohort study. We included 12,624 subjects without baseline NAFLD and 2943 subjects with baseline NAFLD who underwent health check‐up examinations. A total of 10,534 subjects …
How does addition of regular aerobic exercises, influence the efficacy of calorie-restricted diet in patients with non-alcoholi
Hepatology | PBF | H Nikroo et al. | 2017 | Iran | Hepatitis Monthly
Background: Nonalcoholic fatty liver (NAFLD) is a worldwide, leading cause of chronic liver disease, not yet approved medical treatment standards. The aim is to assess the effects of aerobic exercise sand calorie-restricted (CR) diet on many clinical and laboratory findings in patients with Nonalcoholic Steatohepatatis (NASH). Methods: In Randomized controlled trial study, in Mashhad, between February 2010-August 2011, Twenty-five patients with NASH, in ranging ages of 18-55, were randomly selected to be divided in to two groups, who received …