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Serum growth differentiation factor 15 level is associated with muscle strength and lower extremity function in older patients

Geriatrics
Author
Oba et al.
Used Parameters : ASMI

Publication Year : 2020

Country : Japan

Journal : Geriatr Gerontol Int.

Aims Sarcopenia is a serious problem because of its poor prognosis. Growth differentiation factor 15 (GDF15) is associated with mitochondrial dysfunction, inflammation, insulin resistance and oxidative stress, which may play crucial roles for the development of sarcopenia. We aimed to examine whether serum GDF15 level is associated with muscle mass, strength and lower extremity function in older patients with cardiometabolic disease. Methods Serum GDF15 levels were measured in 257 patients with cardiometabolic …
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